The Claudin 16 Polyclonal Antibody, Cy7 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to Claudin 16, and Cldn16. This antibody recognizes Human antigen. The Claudin 16 Polyclonal Antibody, Cy7 Conjugated has been validated for the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors